Newsletter

Filtration/Drying Processes on a Laboratory and Pilot Scale

Products in the pharmaceutical, chemical and processed food sectors are developed on a laboratory scale. Suitable processes must then be developed in order to manufacture the product on a commercial scale. Development departments therefore require miniature versions of the production systems under consideration that are accurate in detail. Only if these provide reproducible results can the process be scaled up to industrial dimensions. It must, however, also be possible to manufacture small batches economically with these pilot-scale systems, typically for clinical studies or to provide product samples.

Rolab

Rolab

Many industrial products are in powder form. Following their manufacture by wet chemical processes, they are precipitated or crystallized out from the solvent. The subsequent steps are usually filtration/ separation, drying and milling, each operation being carried out in a separate specialized unit

Transferring filter cake can prove to be more difficult to transfer from one machine to the next because of the materials properties. The user might run into problems trying to transfer filter cake because the material does not easily flow. If it is essential to avoid a manual operation by the operator, it is therefore a logical step to combine the filtration and drying processes into one unit. In practice, a filter/dryer represents the most cost-effective solution. The slurry is filtered, the filter cake smoothed over, often washed several times and finally dried – all in the same vessel (download of the complete article).

Under the link RoLab you are able to receive further information about the single process steps, as well as about the attributes and advantages of a mobile filter/dryer.

Rolab

Rolab

RoLab    stands    for    “Rosenmund®    Laboratory” and is the name of our latest generation of filter/dryers. The product line    RoLab    is manufactured for use in the laboratory and in pilot-plants. It allows the efficient implementation of filtration and drying trials as well as reliable scale-ups. This multi-purpose equipment also can be integrated in the normal manufacturing process for the production of small batches of active ingredients or intermediates.

The links below lead you to three case studies in English (pdf-file). These short profiles show different application areas and possibilities of RoLab-Filter/dryers in varied equipment.


Would you like to have an answer to your specific questions? Have you got suggestions or comments? Please e-mail us to contact@rosenmund.com. We look forward to receiving your feedbacks.

Best regards

Rosenmund VTA AG

Beat Rhyner

Marketing Manager